Calvert-Lewin is in his first England squad after being selected for this month’s matches against Wales, Belgium and Denmark.
Leicester’s Harvey Barnes and Arsenal’s Bukayo Saka also get first call-ups.
Mason Greenwood and Phil Foden, who were sent home from Iceland last month after breaching coronavirus quarantine guidelines, have been left out.
But Harry Maguire, who was withdrawn from that squad while he faced a court case in Greece, is in the 30-man squad.
Manchester United captain Maguire, 27, was given a suspended prison sentence on the Greek island of Syros after being found guilty of aggravated assault, resisting arrest and repeated attempts of bribery. (BBC)