Arsenal have been drawn against Napoli, while Chelsea will face Slavia Prague in the Europa League quarter-finals.
Villarreal take on fellow Spanish side Valencia with Portuguese team Benfica playing Germany’s Eintracht Frankfurt.
The first and second legs will be played on 11 April and 18 April, with the semi-final draw keeping Arsenal and Chelsea apart should they get that far.
Arsenal boss Unai Emery is chasing a fourth Europa League title as manager after three successive wins at Sevilla. Read more